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Blood Cord Bank An Introduction To Cord Blood Stem Cells

(category: Cardio, Word count: 582)
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Finding a source of primitive stem cells.

There are news reports about the positive impact that research on cord blood stem cells is having on the possible cure for numerous life threatening diseases. But with so many varying reports about it or even factions it is impossible to keep track of all its useful facts. Stem cells show a great level of plasticity which means they can generate and regenerate into many different types of cells and even organs within in our body. Potentially, if they can be removed from the donor and transfused into the patient then in the future, stem cells could be used to cure virtually any illness.

Stem cells are more frequently found in babies or even in embryos although it has been discovered that adult stem cells do exist. To date these have mostly been found in the brain but are dispersed freely amongst millions of other cells making the extraction incredibly difficult.

Cord blood stem cells, on the other hand, are very easy to remove. Because the process is completed after the child has been born and the umbilical cord cut and clamped there is no effect whatsoever on the baby, the parent or the birth itself.

How stem cells become T cells.

T cells are the cells that are responsible for fighting infection in children and are created when stem cells pass through the thymus gland. If the patient does not have an adequate number of effective stem cells in their blood then they will not be able to create the T cells. And subsequently they are much more likely to suffer serious infections. This, in turn, means that cord blood stem cells can be used to recreate T cells as well as other vital cells within the body of your child. The stem cells will then create an army of T cells to fight off infection and leave the body to function in a normal manner. As with a blood transfusion it is imperative to the operation's success that the stem cells transfused are of the same type as the patient's own blood. Using cord blood stem cells belonging to the patient themselves all but guarantees that this will be the case.

Stem cell testing.

The umbilical cord stem cell matrix is called Wharton's jelly and is rich in primitive stem cells. These cells are one that has yet to progress, transform or produce other cells. Primitive stem cells are the most effective type of stem cells that can be used in a transfusion on any patient.

Typically a lot of testing has been done on animals to prove the viability of using stem cells taken from cord blood of newborn babies and amongst the most prominent of these tests, according to the online journal "stem cells", have been tests carried out on pigs. In a human blood cord, similar to a pig umbilical cord, two arteries & vein are found and tests have shown positive results concerned with the storage and potency of the blood. The journal "stem cells" contains a lot of data relating to stem cells and articles on various related topics.

At present leukemia and anemia are the two most common diseases treated with stem cell transfusions although since stem cell research has grown in volume and results diseases such as Parkinson's, Multiple Sclerosis and many different forms of cancer are also showing positive results.

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Mitral Valve Prolapse Mvp A Heart Condition

(category: Cardio, Word count: 466)
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Mitral Valve allows blood to flow in one direction from the atrium (upper chamber) to the ventricle (lower chamber). It is one of the four valves separating different chambers of the heart. Mitral valve causes problem if it doesn't open and close as per its functionality.

It causes blood to leak backwards into the upper chamber of the heart, leading to a 'heart murmur'. This is called as Mitral Valve Prolapse. The functioning of your heart is normal at this point of time. This does not worsen over a period of time, but is one of the main reasons for cardiac problems.

Mitral valve prolapse is very common among women although men are targeted too. It can strike in early adulthood. It is considered to be a hereditary problem. Mitral Valve Prolapse syndrome is also called as dysautonomia.

One of the main reasons which cause an increase in mitral valve prolapse syndrome is stress. The cause of stress can be due to childbirth, drastic events, and life turning experiences and day to day stress in life. Nearly 60% of the patients with MVP do not show symptoms. The other 40% does show some sign, which you should be aware of.

Some Signs and Symptoms of Mitral Valve Prolapse Syndrome

-Irregular Heartbeat

-Fatigue

-Chest Pain

-Racing Heart

-Dizziness

-Headaches

-Shortness of Breath

-Palpitation

-Anxiety

Causes of Mitral Valve Prolapse Syndrome

-Hereditary

-Stress

-Caffeine

-Stimulants

-Sweets

-Alcohol

-Smoking

-Menopause

-Skipping Meals

-Dehydration

Measures to be taken

Complications in this condition are very less. Attributable to the fact, that it does not affect much of your health. But people who suffer from this condition have to take extreme care. You may have to cut down on your physical activity, have a surgery and may be put you on medications - beta blockers.

You may have to follow a strict diet routine. Do not have any stimulants in your diet like coffee, tea, colas and even chocolates. Intake of sugar should come down. Have high-protein snack for afternoons. Drink as much water as you want. Fresh fruit juice is also good.

Regular exercise is good to maintain good health. Do not exert yourself. You should consult your doctor before doing any physical activity. Being aware about your condition would help you from any bacterial infection from any kind of surgery. Inform your doctors in advance about your condition, to avoid complication.

Home Care

Cinnamon helps in reducing high cholesterol and triglycerides. These can be used in your daily diet.

Flax seed oil contributes with good amounts of omega 3 fatty acids. This helps your cardiovascular system by reducing bad cholesterol including lowering blood pressure.

Hawthorn Berries helps with a clean and clear cardiovascular system. It is very good for your heart.

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Six New Year S Resolutions For A Healthy Heart

(category: Cardio, Word count: 330)
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It's that time of year again hence we all promise to make a change for the better. Here's a Los Angeles cardiologist whose wish list of six resolutions for a healthier heart will pay you dividends in 2008. Do you want to prevent heart attack? How about heart surgery recovery tips? Los Angeles Cardiology experts speak out.

1. Reduce stress. Try to take some time for yourself each and every day. Don't lose sight of the big picture. Finally, listen to your body for when it says "enough", it probably is.

2. Stop smoking. Stop smoking. Stop smoking.

3. Eat healthier. Drink low-fat milk. Take baby carrots or cherry tomatoes to work for lunch. Have fish for dinner twice a week. Have one green vegetable with each evening meal. Losing weight if overweight is obvious. Track your weight on paper each morning to chart your progress.

4. Control blood pressure if elevated. Watch your salt intake. Take your blood pressure pills regularly. Monitor on paper your morning blood pressure and review them with your doctor at follow-up visits.

5. Lower elevated cholesterol. Know your LDL ("bad" cholesterol) and HDL ("good" cholesterol) levels. Follow a prudent low cholesterol diet. Take your medications if prescribed regularly.

6. Exercise regularly. Even small amounts of daily exercise can provide significant heart benefits. Try an activity that can fit into your daily routine...it doesn't have to be a gym or a trainer...walking with a pedometer for 2 or 3 miles a day each morning would do just fine.

Enjoy the Holidays and have a happy and healthier New Year !

Mason Weiss, M.D., F.A.C.C., is a triple board certified physician with certification in internal medicine, general cardiology, and interventional cardiology. He has practiced medicine for 23 years and is a physician partner with the highly regarded APEX Cardiology team of physicians located at 501 East Hardy Street, Suite 200, Inglewood, California 90301 (310) 672-3900

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Malignant Hypertension Causes Symptoms And Treatment

(category: Cardio, Word count: 691)
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Malignant Hypertension and accelerated high blood pressure are two emergency conditions which should be treated promptly. Both conditions have same outcome and therapy. However Malignant hypertension is a complication of high blood pressure characterized by very elevated high blood pressure, and organ damage in the eyes, brain, lung and/or kidneys. It differs from other complications of hypertension in that it is accompanied by papilledema. (Edema of optic disc of eye) Systolic and diastolic blood pressures are usually greater than 240 and 120, respectively. While Accelerated high blood pressure is condition with high blood pressure, target organ damage, on fundoscopy we have flame shaped hemorrhages, or soft exudates, but without papilledema.

There are two things. Hypertensive Urgency and Hypertensive emergency. In hypertensive urgency we don't see any target organ damage while in emergency we see target organ damage along with high blood pressure greater than systolic >220. Now depending upon target organ damage you will decide whether you have hypertensive emergency or urgency. It is essential to bring down high blood pressure in hypertensive emergency immediately, while in urgency, bring down blood pressure very rapidly is not required.

Pathogenesis of malignant hypertension is fibrinoid necrosis of arterioles and small arteries. Red blood cells are damaged as they flow through vessels obstructed by fibrin deposition, resulting in microangiopathic hemolytic anemia. Another pathologic process is the dilatation of cerebral arteries resulting in increased blood flow to brain which leads to clinical manifestations of hypertensive encephalopathy. Common age is above 40 years and it is more frequent in man rather than women. Black people are at higher risk of developing hypertensive emergencies than the general population.

Target organs are mainly Kidney, CNS and Heart. So symptoms of Malignant hypertension are oligurea, Headache, vomiting, nausea, chest pain, breathlessness, paralysis, blurred vision. Most commonly heart and CNS are involved in malignant hypertension. The pathogenesis is not fully understood. Up to 1% of patients with essential hypertension develop malignant hypertension, and the reason some patients develop malignant hypertension while others do not is unknown. Other causes include any form of secondary hypertension; use of cocaine, MAOIs, or oral contraceptives; , beta-blockers, or alpha-stimulants. Renal artery stenosis, withdrawal of alcohol, pheochromocytoma {most pheochromocytomas can be localized using CT scan of the adrenals}, aortic coarctation, complications of pregnancy and hyperaldosteronism are secondary causes of hypertension. Main Investigations to access target organ damage are complete renal profile, BSR, Chest Xray, ECG, Echocardiography, CBC, Thyroid function tests.

Management:

Patient is admitted in Intensive Care Unit. An intravenous line is taken for fluids and medications. The initial goal of therapy is to reduce the mean arterial pressure by approximately 25% over the first 24-48 hours. However Hypertensive urgencies do not mandate admission to a hospital. The goal of therapy is to reduce blood pressure within 24 hours, which can be achieved as an outpatient department. Initially, patients treated for malignant hypertension are instructed to fast untill stable. Once stable, all patients with malignant hypertension should take low salt diet, and should focus on weight lowering diet. Activity is limited to bed rest until the patient is stable. Patients should be able to resume normal activity as outpatients once their blood pressure has been controlled.

Hospitalization is essential until the severe high blood pressure is under control. Medications delivered through an IV line, such as nitroglycerin, nitroprusside, or others, may reduce your blood pressure. An alternative for patients with renal insufficiency is IV fenoldopam. Beta-blockade can be accomplished intravenously with esmolol or metoprolol. Labetalol is another common alternative, providing easy transition from IV to oral (PO) dosing. Also available parenterally are enalapril, diltiazem, verapamil, Hydralazine is reserved for use in pregnant patients as it also increases uterine profusion, while phentolamine is the drug of choice for a pheochromocytoma crisis. After the severe high blood pressure is brought under control, regular anti-hypertensive medications taken by mouth can control your blood pressure. The medication may need to be adjusted occasionally.

Remember, It is very necessary to control malignant hypertension, otherwise it can lead to life threatening conditions like Heart Failure, Infarction, Kidney failure and even blindness.

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Women Need To Know More About Treating Heart Disease

(category: Cardio, Word count: 382)
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Although 73 percent of women know how to prevent heart disease, many are unaware of how to treat it once a diagnosis has been made.

In a survey of 1,979 women over age 35, only 55 percent said they understand how to treat heart disease. Respondents often incorrectly named prevention techniques such as exercise and healthy eating as treatment options, and less than 10 percent named actual treatments such as angioplasty and stent placement.

Hispanics and African-Americans, both considered high-risk groups for heart disease, were twice as likely as Caucasian women to say they did not know any treatments at all.

The survey was conducted by the "Healthy From the Heart" campaign sponsored by the National Women's Health Resource Center and Cordis Corp. The campaign encourages women to learn about treatment options for coronary artery disease, the most common type of heart disease, so they can make better decisions if diagnosed.

"The good news is that women are aware that they are at risk for heart disease. The bad news is that they are overly confident in their ability to prevent it and treat it," said Dr. Cindy Grines, an interventional cardiologist with William Beaumont Hospital in Royal Oaks, Mich. "Women must realize that education is the key to conquering the threat of coronary artery disease. There are a variety of treatment options now available."

The most common procedure for treating coronary artery disease is balloon angioplasty with a coronary stent. Angioplasty widens narrowed arteries by threading a balloon-tipped catheter through the arm or groin artery to the blocked artery in the heart. The balloon is inflated to compress the plaque against the artery walls, which in turn expands the blood vessel so blood can flow more easily.

Scientific advances have led to the development of the drug-eluting stent, a tiny mesh scaffold that props the artery open while releasing small amounts of a particular drug, such as sirolimus, inside the artery over a period of time. This helps keep plaque from reforming and helps prevent repeat blockage from occurring inside the blood vessel.

Coronary bypass surgery is another treatment option. While more invasive, it is a safe and effective treatment for patients who may not qualify for angioplasty and stent insertion.

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Know Your Heart Health

(category: Cardio, Word count: 431)
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We all know that keeping up with our heart health is an important thing to do. We all know that there are a wide variety of factors that cause heart problems, and we should know by now that there are some basic ways to help protect the health of our hearts. What many people do not realize, however, is that keys to their heart health may be different than keys to the heart health of others.

There are almost as many strategies and tips for having good heart health as there are people with hearts in the world. It is important that each person takes the time to learn about his or her own heart health and to learn about the possible methods of ensuring heart health for years to come.

One of the best ways for anyone to become familiar with the needs of their heart is to see a physician. Schedule a visit to see your doctor and plan to discuss your heart health with him or her. If you can think of any questions or concerns you have regarding your heart health, write them down and bring them along. It will also be very helpful if you have a record of your extended family's heart health history. It is likely that your physician will want to discuss more than just your own heart health. He or she will want to look for patterns or trends that have affected other people you're related to.

A physician can help you determine not only the current health of your heart, but also give you a better understanding of specific things you can do to help prevent heart attack or heart disease. For some people, the most significant factor in achieving and maintaining heart health is to change their diet. The foods we choose to put into our bodies affect our heart health in more ways than we know. Eating large amounts of sugar, carbohydrates or processed foods will eventually take their toll on our heart health. Your physician can set you up with a dietician who specializes in creating unique diet plans that promote heart health.

For other people, it is their exercise and physical fitness habits that a physician will address. Heart health can be significantly altered based upon a person's level of exercise. Your physician will be able to help you create a fitness plan that will be effective for you and your heart health needs.

It is never too late to take your heart health seriously. Make an appointment to see your physician today.

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Signs Of High Blood Pressure

(category: Cardio, Word count: 310)
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High blood pressure is known as a silent killer. And probably most don't even think about their blood pressure. However, high blood pressure can be quite fatal. There are some symptoms that can indicate that you have high blood pressure, and can prevent you from having a stroke. So continue reading as it might save your life or the life of someone you know.

Some of the typical signs of high blood pressure are headaches, dizziness, pounding in the ears and a bloody nose. But some people experience a small pain in the back of their head or have an increase in urination.

Though an increase in urination could mean your blood sugar is really high, if you are diabetic. That's why it's hard to see the signs. But if you are diabetic and you are experiencing an increase in urination and headaches, then just check your blood sugar and see if that is the cause. If it is not then you can rule out high blood sugar, and find out if you have high blood pressure.

Adding salt to your diet can also inflate your risk of having blood pressure. Having too much salt in your diet can increase your blood pressure. Talk to your doctor if need to cut down on your salt intake.

But if you have to cut down on the salt, you can use many other herbs instead of salt. Garlic, chives, and onions are good alternatives. Cutting down on the slat is not so bad, just think of the alternative.

You shouldn't ignore high blood pressure; it can be very fatal if unchecked. The result could be you having a stroke. A stroke can be very deadly and limit your movements. So go to the doctor and see if you have high blood pressure.

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Heart Failure Frequently Asked Questions

(category: Cardio, Word count: 325)
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According to the American Heart Association, nearly five million Americans are living with heart failure and 550,000 new cases are diagnosed each year. Heart failure is a serious condition that often is misunderstood. The questions below are intended to help clear up some misperceptions about this condition and its complications.

Q. What is heart failure?

A. Heart failure does not mean that your heart has stopped or is about to stop. It is a serious condition in which the heart doesn't pump blood through your body as well as it should.

Your heart still beats, but it pumps less nutrient- and oxygen-rich blood to the rest of your body. Because of this, heart failure can make you feel tired or weak. Heart failure also can cause swelling and fluid buildup in your legs, feet and even your lungs. Fluid buildup in your lungs often is referred to as "congestion," which is why heart failure is sometimes called "congestive heart failure (CHF)." At times, patients may require hospitalization to treat a worsening, or an acute episode, of their heart failure symptoms.

Q. What are the symptoms of heart failure?

A. Some symptoms of heart failure include shortness of breath, frequent coughing, increased heart rate, heart palpitations (your heart may feel like it is racing), fatigue, weakness, swollen ankles and legs, loss of appetite and weight gain. Patients who experience acute episodes of their heart failure symptoms also may have extreme shortness of breath that leaves them gasping for air. Since they may have fluid buildup in their lungs, they may feel as though they are drowning.

Q. How are acute episodes of heart failure treated?

A. There are some common intravenous (IV) drugs that are commonly given to patients in hospitals to treat acute episodes of heart failure. They include diuretics, inotropes and IV vasodilators.

Please talk to your healthcare professional for more information.

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Good Diet For High Blood Pressure And Hypertension

(category: Cardio, Word count: 937)
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This article will furnish you comprehensive Dietary Advice For Prehypertensive and Hypertensive Blood Pressure Levels. Here you will find Diet Tips To Reduce Blood Pressure

Diet For High Blood Pressure and Hypertension, Relation Between Diet and Blood Pressure

If you have Bad eating habits then it contributes significantly to unhealthily high blood pressure levels, even in middle age, when blood pressure levels typically rise as part of the aging process. Whether or not you are taking antihypertensive drugs, the need to make dietary improvements (eg. follow a healthy low-fat diet) is frequently at the top of a doctor's list of recommendations to reduce or prevent the onset of high blood pressure. Before outlining the best type of diet for hypertension, let's take a brief look at health consequences of raised blood pressure.

Hazards of Hypertension & High Blood Pressure

In under developed as well as developed countries, an estimated 20-40 percent of all adults suffer from persistent high blood pressure. High blood pressure puts a strain on the heart causing atherosclerosis(Thickenning of vessels). Result is damage to heart, Coronary artery disease, Kidney failure, Strok, Eye damage. Choice is yours, try to save these vital organs by controlling your BP. Remember Hypertension is a silent Killer, it shows its effects silently and when you come to know that you have BP, by that time hypertension often affects your vital organs.

Normal Blood Pressure Levels vs. Prehypertensive and Hypertensive

Normal blood pressure of an healthy adult at rest, is 120 (systolic) over 80 (diastolic) or less. Blood pressure levels greater than 120/80 and below 140/90 are at prehypertensive stage, while levels above 140/90 are considered hypertensive stage. Both prehypertensive and hypertensive subjects should make diet, exercise and lifestyle changes to reduce or prevent the onset of hypertension and reduce the risk of heart disease.

Weight increases blood Pressure

Over weight persons will be having high blood pressure. Weight reduction significantly decreases blood pressure.People with obesity double their risk of developing the disorder. In addition, roughly 7 out of 10 obese adults suffer from high blood pressure. If you lose even 10 pounds can produce noticeable improvements.

Dietary Advice and Tips For High Blood Pressure

If you have high blood pressure and not overweight, here are few tips to control your BP.

Choose A Healthy Balanced Diet

If you want to reduce your blood pressure, your diet should be rich in fruits, vegetables, and low-fat dairy foods, while low in saturated and trans-fats. It should also be low in cholesterol, high in fiber, calcium,potassium and magnesium, and moderately high in protein. The American Heart Association and U.S. government recommend the Dietary Approaches to Stop Hypertension (DASH) diet as a good diet guide to reduce blood pressure.

First thing is to Reduce Your Intake of Sodium (Salt)

How salt intake increases blood pressure. Eating too much salt or sodium-rich foods leads to a greater uptake of fluid and causes greater retension of water inside body, leads to volume overloard and High blood presure. It also places extra strain on the arterioles (blood vessels that dilate/constrict to regulate blood pressure and blood flow). Both these effects lead to higher blood pressure. The Recoomended daily dose for sodium for most people is 2,400 mg.

You can Reduce Sodium Intake

How can you decrease sodium intake? Eat less pre-cooked or processed food, and eat more fresh food. Sodium is found naturally in fresh foods like grains, fruits, vegetables, meats, nuts, and dairy products, but in much lower quantities than in processed foods (eg. packet, bottled or canned food).

High Sodium Foods

These foods typically have a high sodium content. In order not to exceed the RDA, either avoid them altogether, or choose low-sodium varieties.

Sauces: baking soda, barbecue sauce, catsup, garlic salt, mustard, onion salt,Soy sauce, steak sauce, salad dressing, baking powder, mustard, onion salt, seasoned salts like lemon pepper, bouillon cubes, meat tenderizer, and monosodium glutamate.

Salted Snacks: peanuts, pretzels, pork rinds.Tortilla chips, corn chips

Soup: instant soups, Regular canned soups.

Pickled Food: Olives, or sauerkraut, Herring, pickles, relish,

Meats: smoked or cured meats (containing sodium-nitrite) such as bacon, bologna, hot dogs, ham, corned beef, luncheon meats, and sausage, Hogmaws, ribs, and chitterlings,.

Dairy: Most cheese spreads and cheeses.

Drinks: club soda, saccharin-flavored soda,

Cereals: Instant hot cereals, Regular ready to eat cold cereals,

Ready-to-Eat: boxed mixes like rice, scalloped potatoes, macaroni and cheese and some frozen dinners, pot pies and pizza. Quick cook rice, instant noodles,

Fats: Butter, fatback, and salt pork.

Check Labels of Food Containers:

Choose those foods which labeled as low-sodium, very low sodium, or salt-free. Check food labels for words that indicate a high sodium content, including: sodium nitrite, sodium proprionate, disodium phosphate, and sodium sulfate., monosodium glutamate (MSG), sodium benzoate, sodium hydroxide,

Lower Sodium Eating Habits

Do not add extra salt when cooking or preparing meals. Cook with more herbs and spices.

Do not have salt on the table while eating do not add salt on salad.

If you cook with salt, switch to chili, ginger and lemon juice for flavoring.

If you eat cured/smoked meats, switch to fresh cold meats.

If you eat ready-to-serve breakfast cereal, choose low-sodium types of cereal.

Rinse before eating, If you eat tuna, salmon, sardines, or mackerel canned in water.

If you eat soup, switch to low-sodium or fresh soups.

If you cook with whole milk or fat diet, switch to 1 percent or skimmed buttermilk.

Remember taking less salt diet, Your BP will be in normal Limits.

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